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www.Omega3Advantage.com brings you earth friendly ecological friendly products to make life better for humans and the planet.

We are committed to conduct our business in an ethically and socially responsible way. The Calamarine range of products adheres to these principles:

• Produced solely from by-products of existing food production of Calamari, not one creature is removed from the sea to produce these oils.
• To a large degree line fishing for calamari performed by local artisan vessels
• No netting or by-product catch at all. No dolphins harmed, etc.

• General health
• Improving n-3/n-6 ratio
• Low risk cardiovascular prevention
• High risk cardiovascular/Atherosclerosis
• Inflammatory diseases
• Macular degeneration
• Alzheimer dementia
• Maternal-Childhood development

Find out more.

de Lorgeril M, Salen P.

Source

PRETA-TIMC, Equipe Coeur & Nutrition, CNRS UMR 5525-UJF-INP, University Joseph Fourier, Grenoble, France. michel.delorgeril@ujf-grenoble.fr

Abstract

Consumption of a traditional Mediterranean diet and n-3 polyunsaturated fatty acids (PUFAs) was shown to be effective in reducing the complications of coronary heart disease in randomised controlled trials. Epidemiological studies and controlled trials indicate that plant- and sea-derived n-3 PUFAs are likely to be important mediators of the protection provided by traditional Mediterranean diets. Of note, consumption of marine n-3 PUFAs from fish and other seafood is high in certain Mediterranean countries (Spain, Portugal), but quite low in others (Italy, Greece). A relative insufficiency of dietary marine n-3 PUFAs among Italians might in part explain the results of the GISSI-Prevenzione trial, in which a modest supplementation of eicosapentaenoic acid + docosahexaenoic acid ( approximately 850 mg/day) produced striking reductions in coronary heart disease death (-30%) and sudden cardiac death (-45%) among patients with known heart disease. The protection provided by n-3 PUFAs from both plant and marine sources may be partly dependent on other dietary factors. Plant and marine n-3 PUFAs are likely to be major mediators of the protective effect provided by traditional Mediterranean diets.

PMID:

17876197

[PubMed - indexed for MEDLINE]

Pathophysiology. 2007 Oct;14(2):127-32. Epub 2007 Jun 28.

n-3 PUFAs-From dietary supplements to medicines.

Fedacko J, Pella D, Mechírová V, Horvath P, Rybár R, Varjassyová P, Vargová V.

Source

Centre of Preventive and Sports Medicine L. Pasteur Hospital and P.J. Safarik University, Trieda SNP 1, 041 90 Kosice, Slovakia.

Abstract

Although there has been a great progress in the prevention of cardiovascular diseases, the mortality of patients with acute myocardial infarction (AMI) still remains high. One of the most important underlying causes explaining this phenomenon is the sudden cardiac death. Nearly half of all cardiovascular deaths in the USA each year is attributed to this unpredictable and unexpected complication of AMI. Hence, there is an urgent medical need for a targeted therapy to reduce the incidence of sudden cardiac death. Since 1980 there have been several epidemiological and other studies concerning the benefits of n-3 polyunsaturated fatty acids (n-3 PUFAs) in cardiovascular health and prevention. Results from one of the largest studies, GISSI Prevenzione Trial show that adding the n-3 PUFAs to standard therapy of patients who survived AMI reduces sudden cardiac death (44% risk reduction, p=0.0006). In addition, significant decline in all-cause cardiovascular mortality (21% risk reduction, p=0.0064) further emphasizes the role of n-3 PUFA in cardiovascular prevention. To date, beneficial effects of n-3 PUFA are attributed to their antiarrhythmic, lipid lowering, antithrombotic and anti-inflammatory properties. To conclude, EPA and DHA improve the prognosis of cardiovascular patients in the secondary prevention of sudden cardiac death without any documented side effects.

PMID:

17604611

[PubMed]

Historical overview of n-3 fatty acids and coronary heart disease.

Leaf A.

Source

Massachusetts General Hospital and the Harvard Medical School, Boston, MA 02114, USA.

Abstract

The first evidence that fish oil fatty acids might have a beneficial effect on coronary heart disease came from the discovery that Greenland Eskimos, who have a diet high in n-3 fatty acids, have a lower mortality from coronary heart disease than do Danes and Americans. Long-chain polyunsaturated fatty acids are essential in our diets and can be classified in 2 groups: n-6 fatty acids found in plant seeds and n-3 fatty acids found in marine vertebrates. Further evidence of n-3 benefits to human health include a 1989 study demonstrating a 29% reduction in fatal cardiac arrhythmias among subjects with a recent myocardial infarction who had been advised to consume fish oil. The GISSI-Prevenzione Trial found a significant reduction in relative reduction of death, cardiac death, nonfatal myocardial infarction, and stroke in subjects consuming n-3 fatty acids. In a recent study, subjects with implanted cardiac defibrillators (ICDs) at high risk for fatal ventricular arrhythmias were randomly assigned to four 1-g capsules of either an ethyl ester concentrate of n-3 fatty acids or olive oil daily for 12 mo. Subjects receiving n-3 who thus had significantly higher levels of eicosapentaenoic acid and docosahexaenoic acid in their red blood cell membranes showed a longer time to first ICD events and had a significantly lower relative risk of having an ICD event or probable event (P = 0.033). These studies demonstrate that fish oil fatty acids have beneficial effects on coronary heart disease.

PMID:

18541598

[PubMed - indexed for MEDLINE]

Biomed Pharmacother. 2002 Oct;56(8):365-79.

The importance of the ratio of omega-6/omega-3 essential fatty acids.

Simopoulos AP.

Source

The Center for Genetics, Nutrition and Health, Washington, DC 20009, USA. cgnh@bellatlantic.net

Abstract

Several sources of information suggest that human beings evolved on a diet with a ratio of omega-6 to omega-3 essential fatty acids (EFA) of approximately 1 whereas in Western diets the ratio is 15/1-16.7/1. Western diets are deficient in omega-3 fatty acids, and have excessive amounts of omega-6 fatty acids compared with the diet on which human beings evolved and their genetic patterns were established. Excessive amounts of omega-6 polyunsaturated fatty acids (PUFA) and a very high omega-6/omega-3 ratio, as is found in today’s Western diets, promote the pathogenesis of many diseases, including cardiovascular disease, cancer, and inflammatory and autoimmune diseases, whereas increased levels of omega-3 PUFA (a low omega-6/omega-3 ratio) exert suppressive effects. In the secondary prevention of cardiovascular disease, a ratio of 4/1 was associated with a 70% decrease in total mortality. A ratio of 2.5/1 reduced rectal cell proliferation in patients with colorectal cancer, whereas a ratio of 4/1 with the same amount of omega-3 PUFA had no effect. The lower omega-6/omega-3 ratio in women with breast cancer was associated with decreased risk. A ratio of 2-3/1 suppressed inflammation in patients with rheumatoid arthritis, and a ratio of 5/1 had a beneficial effect on patients with asthma, whereas a ratio of 10/1 had adverse consequences. These studies indicate that the optimal ratio may vary with the disease under consideration. This is consistent with the fact that chronic diseases are multigenic and multifactorial. Therefore, it is quite possible that the therapeutic dose of omega-3 fatty acids will depend on the degree of severity of disease resulting from the genetic predisposition. A lower ratio of omega-6/omega-3 fatty acids is more desirable in reducing the risk of many of the chronic diseases of high prevalence in Western societies, as well as in the developing countries, that are being exported to the rest of the world.

Endocr Metab Immune Disord Drug Targets. 2011 Jun 8. [Epub ahead of print]

Role of n-3 Long chain Polyunsaturated Fatty Acids in Reducing Cardio-Metabolic Risk Factors.

Abeywardena MY, Patten GS.

Source

CSIRO Food & Nutritional Sciences, Kintore Avenue, Adelaide, SA 5000, Australia. mahinda.abeywardena@csiro.au.

Abstract

Cardiovascular disease is the leading cause of mortality in many economically developed nations, and its incidence is increasing at a rapid rate in emerging economies. Diet and lifestyle issues are closely associated with a myriad of cardiovascular disease risk factors including abnormal plasma lipids, hypertension, insulin resistance, diabetes and obesity, suggesting that diet-based approaches may be of benefit. Omega-3 longchain-polyunsaturated fatty acids (?3 LC-PUFA) are increasingly being used in the prevention and management of several cardiovascular risk factors. Both the ?3 and ?6 PUFA families are considered essential, as the human body is itself unable to synthesize them. The conversion of the two precursor fatty acids – linoleic acid (18:2?6) and ?-linoleic acid (?18:3?3) – of these two pathways to longer (?C(20)) PUFA is inefficient. Although there is an abundance of ?6 PUFA in the food supply; in many populations the relative intake of ?3 LC-PUFA is low with health authorities advocating increased consumption. Fish oil, rich in eicosapentaenoic (EPA, 20:5?3) and docosahexaenoic (DHA, 22:6?3) acids, has been found to cause a modest reduction in blood pressure at a dose level of >3g/d both in untreated and treated hypertensives. Whilst a multitude of mechanisms may contribute to the blood pressure lowering action of ?3 LC-PUFA, improved vascular endothelial cell function appears to play a central role. Recent studies which evaluated the potential benefits of fish oil in type-2 diabetes have helped to alleviate concerns raised in some previous studies which used relatively large dose (5-8 g/d) and reported a worsening of glycemic control. Several meta-analyses have confirmed that the most consistent action of ?3 LC-PUFA in insulin resistance and type-2 diabetes is the reduction in triglycerides. In some studies, fish oil has been found to cause a small rise in LDL-cholesterol, but a change in the LDL particle size, from the smaller more atherogenic form to the larger, less damaging particle size, have also been noted. ?3 LC-PUFA are effective modulators of the inflammation that accompanies several cardio-metabolic abnormalities. Taking into consideration the pleiotropic nature of their actions, it can be concluded that dietary supplementation with ?3 LC-PUFA will lead to improvements in cardio-metabolic health parameters. These fatty acids pose only minor side effects and more importantly, do not interact adversely with the common drug therapies used in the management and treatment of hypertension, dyslipidemia, type-2 diabetes, and obesity/metabolic syndrome, but in some instances work synergistically, thereby providing additional cardiovascular benefits.

PMID: 21651471 [PubMed - as  supplied by publisher]

Curr Opin Lipidol. 2011 Oct 7. [Epub ahead of print]

Novel developments in omega-3 fatty acid-based strategies.

Davidson MH, Kling D, Maki KC.

Source

aUniversity of Chicago Pritzker School of Medicine, Chicago, Illinois bOmthera Pharmaceuticals, Inc., Bedminster, New Jersey cProvident Clinical Research, Biofortis-North America, Glen Ellyn, Illinois, USA.

Abstract

PURPOSE OF REVIEW:

Omega-3 polyunsaturated fatty acids (n-3 PUFAs) have been attributed with several health benefits, including triglyceride lowering and cardiovascular disease risk reduction. This review focuses on new prescription omega-3 fatty acid products in development and recently published data regarding omega-3 fatty acid effects on arrhythmias, heart failure, and platelet inactivation.

RECENT FINDINGS:

A free fatty acid form of n-3 PUFA was found to produce a four-fold higher area under the plasma n-3 PUFA curve than prescription omega-3-acid ethyl esters in patients on a low-fat diet. Eicosapentaenoic acid ethyl esters reduced triglyceride without significantly elevating LDL cholesterol in patients with severe hypertriglyceridemia and in those with mixed dyslipidemia. Recent investigations of n-3 PUFA effects on ventricular and atrial arrhythmias, including studies in patients with implanted defibrillators, failed to demonstrate a significant benefit. However, increased fatty fish or n-3 PUFA consumption was associated with a lower rate of hospitalization in heart failure patients. A further important finding was potentiation of the antiplatelet response when n-3 PUFAs were added to aspirin?+?clopidogrel.

SUMMARY:

Although n-3 PUFA therapy continues to show promise in the prevention and management of cardiovascular diseases, further research is necessary to more fully elucidate its role in specific disorders.

Am J Clin Nutr. 2008 Jun;87(6):1981S-90S.

Role of n-3 fatty acids in the treatment of hypertriglyceridemia and cardiovascular disease.

Jacobson TA.

Source

Office of Health Promotion and Disease Prevention, the Department of Medicine, Emory University, Atlanta, GA 30303, USA. tjaco02@emory.edu

Abstract

n-3 Fatty acids (FAs) when used in doses of 3-4 g/d eicosapentaenoic acid and docosahexaenoic acid have profound effects on triacylglycerol (TG) concentrations. The mechanism for their TG reduction relates to their favorable effects on reducing hepatic production and secretion of VLDL and VLDL apolipoprotein B particles, along with favorable effects on plasma lipolytic activity through lipoprotein lipase-mediated clearance, as well as stimulation of beta-oxidation of other FAs in the liver. Their hypotriglyceridemic properties are related to both the dose of n-3 FAs used and the baseline TG concentrations of the population. In patients with TG concentrations >500 mg/dL, 4 g n-3 FAs have been shown to reduce TGs by 45%, VLDL by 42%, and non-HDL by 10.2%. A recent pooled meta-analysis with multiple doses of n-3 FAs ranging from 0.8 to 5.4 g revealed changes in TGs of -27 mg/dL (95% CI: -33, -20), in HDL of +1.6 mg/dL (95% CI: + 0.8, +2.3), and in LDL cholesterol of +6 mg/dL (95% CI: + 3, +8). The clinical uses of n-3 FAs include treatment of severe and moderate hypertriglyceridemia, use in statin-treated patients with elevated TG concentrations or non-HDL cholesterol (mixed hyperlipidemia), and use in the secondary and primary prevention of cardiovascular disease. Existing large-scale clinical trials such as the GISSI-Prevenzione Study and JELIS with low doses of n-3 FAs (1-2 g) show clinical benefit in reducing coronary heart disease without substantial changes in concentrations of TGs or other lipids. Future clinical trials need to determine whether the TG-lowering doses of n-3 FAs (3-4 g/d) result in additional risk reduction.

Efficacy of n-3 polyunsaturated fatty acids according to clinical characteristics of patients with recent myocardial infarction: insights from the GISSI-Prevenzione trial.

Marchioli R, Marfisi RM, Borrelli G, Chieffo C, Franzosi MG, Levantesi G, Maggioni AP, Nicolosi GL, Scarano M, Silletta MG, Schweiger C, Tavazzi L, Tognoni G.

Source

Consorzio Mario Negri Sud, Santa Maria Imbaro (CH), Italy. marchioli@negrisud.it

Abstract

The GISSI-Prevenzione trial established the efficacy of n-3 polyunsaturated fatty acids (PUFAs) for reducing mortality in patients after recent myocardial infarction. The generalisability of such results to clinical practice could vary according to other individual patient characteristics. We analysed the GISSI-Prevenzione database to assess whether other major risk factors, comorbidities, dietary habits, or medications could interact with the efficacy of n-3 PUFA treatment to reduce total mortality. We found no evidence that concomitant disease states, habits, or interventions altered the therapeutic benefit of n-3 PUFA consumption in survivors of recent myocardial infarction.

PMID:

17876196

[PubMed - indexed for MEDLINE]

Curr Atheroscler Rep. 2007 Aug;9(2):145-53.

Beyond lipids: the role of omega-3 fatty acids from fish oil in the prevention of coronary heart disease.

Jacobson TA.

Source

Department of Medicine, Emory University, 49 Jesse Hill Jr Drive SE, Atlanta, GA 30303, USA. tjaco02@emory.edu

Abstract

Omega-3 fatty acid therapy shows great promise in the secondary prevention of coronary artery disease. A meta-analysis of recent omega-3 trials shows reductions of coronary heart disease mortality of 36% (95% CI, 20%-50%; P<0.001) and total mortality of 17% (95% CI, 0%-32%; P=0.046). Some of the potential mechanisms for cardiovascular protection include a reduction in cardiac arrhythmias and plaque stabilization. Since the publication of the landmark GISSI-Prevenzione trial, there have been three major intermediate cardiovascular endpoint studies in patients with implantable cardioverter defibrillators (ICDs) and one large trial, the Japan EPA Lipid Interventional Study (JELIS) trial, which involved 18,645 Japanese patients in primary and secondary prevention. The three studies with ICD patients have been mixed, with favorable trends toward reduction in the incidence of ventricular arrhythmias in some but not all of the studies. Results of the recent JELIS trial in a Japanese population already consuming a high intake of omega-3 fatty acids showed a 19% risk reduction in major coronary events. Most of the reductions were in unstable angina and nonfatal coronary events, but not in sudden death and cardiovascular mortality. The totality of evidence suggests greater benefits with omega-3 fatty acids in secondary prevention than primary prevention and in populations consuming low amounts of omega-3 fatty acids

Herz. 2006 Dec;31 Suppl 3:83-95.

Highly purified omega-3 polyunsaturated fatty acids in clinical development.

Vik H.

Source

Pronova Biocare, Lysaker, Norway.

Abstract

Highly purified omega-3 polyunsaturated fatty acids (PUFAs) (Omacor) is the focus of an extensive and ambitious clinical development program that seeks to build on the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell’Infarto Miocardico (GISSI)-Prevenzione study. Studies currently in progress include very large clinical outcome trials designed to evaluate the impact of omega-3 PUFAs on death and major morbid events in defined patient populations such as individuals with heart failure or diabetes, specialist investigations in very high-risk populations such as patients requiring hemodialysis, and a range of specialized studies concerned with mechanisms of action and effects on biochemical and laboratory indices. The emergence of results from these studies can be expected to define a spectrum of indications for omega-3 PUFAs in the management of cardiovascular and renal disease.

Herz. 2006 Dec;31 Suppl 3:74-82.

A multi-country health-economic evaluation of highly concentrated n-3 polyunsaturated fatty acids in the secondary prevention after myocardial infarction.

Lamotte M, Annemans L, Kawalec P, Zoellners Y.

Source

HEDM-IMS, Bruxelles, Belgium.

Abstract

Patients who survive an acute myocardial infarction (MI) are at increased risk of subsequent major cardiovascular events and cardiac (often sudden) death. The use of highly concentrated and purified omega-3 polyunsaturated fatty acids (n-3 PUFAs), in addition to standard secondary prevention after MI, results in a significant reduction in the risk of sudden death. This study assessed the cost-effectiveness of adding n-3 PUFAs to the current secondary prevention treatment after acute MI in 5 countries: Australia, Belgium, Canada, Germany, Poland. Based on the clinical outcomes of GISSI-Prevenzione (MI, stroke, revascularisation rate and mortality), a decision-model was built in DataPROTM. The implications of adding n-3 PUFAs to standard treatment in patients with a recent history of MI were analysed from the health care payer’s perspective. The time horizon was 3.5 years (identical to GISSI-Prevenzione). Event costs were based on literature data. Life expectancy data for survivors of cardiac disease were taken from the Saskatchewan database and then country-adjusted. Results are expressed as extra cost (Euro) per life-year gained (LYG). Annual discounting of 5% was applied to health effects and costs. Treatment with highly concentrated n-3 PUFAs yielded between 0.260 (Poland) and 0.284 (Australia) LYG, at an additional cost of Euro 807 (Canada) to Euro 1,451 (Belgium). The incremental cost-effectiveness ratio (ICER) varied between Euro 2,867 (Canada) and Euro 5,154 (Belgium) per LYG. Sensitivity analyses on effectiveness, cost of complications and discounting proved the robustness of the results. A 2nd order Monte Carlo simulation based on the 95% CIs obtained from GISSI showed that highly concentrated n-3 PUFAs are cost-effective in more than 99% of patients (assuming societal willingness to pay threshold of Euro 20,000/LYG). Including health care costs incurred during the remaining life-years considerably increased total costs, but had no impact on the ICER-based treatment recommendation. Adding highly concentrated n-3 PUFAs to standard treatment in the secondary prevention after MI appears to be cost-effective in the 5 countries studied.

Calamarine: Use the Coupon Code from the Ad in the September issue of the Health Quest Newspaper to get your first bottle sent to you free.

Subsequent shipments of will proceed automatically for the very low discounted price of only $24.95 (that’s half off the retail price.) You may cancel at anytime. Take good care of your body and your body will take good care of you! Univeral law!

Dear Health Quest Reader,

Your First Bottle of Calamarine is Free!

Calamarine: Use the Coupon Code from the Ad in the September issue of the Health Quest Newspaper to get your first bottle sent to you free. Subsequent shipments will proceed automatically for the very low discounted price of $24.95 (that’s half off the retail price.) You may cancel at anytime. Take good care of your body and your body will take good care of you.

Limit ONE Free Bottle of Calamarine per Household! Thank you.

On this first bottle of calamarine, there is a shipping charge of $4.95. On subsequent shipments, shipping is waived.

I found the following article on dhaomega.org.

INTRODUCTION TO OMEGA-3

There has been a dramatic surge in interest recently, amongst the public and health professionals alike, of the health effects of omega-3 fatty acids derived from fish/fish oils – consisting of docosahexaenoic acid (DHA) plus eicosapentaenoic acid (EPA). DHA is required in high levels in the brain and retina as a physiologically-essential nutrient to provide for optimal neuronal functioning (learning ability, mental development) and visual acuity, in young and old alike. DHA plus EPA are both considered to have beneficial effects in the prevention and management of cardiovascular disease plus associated risk factors as well as other chronic disorders. Whereas considerable amounts of the plant-derived omega-3 fatty acid known as a-linolenic acid (ALA) is consumed daily in North America (approximately 2 g/day), the physiologically-essential nutrient, DHA, is consumed at much smaller levels (approximately 80 mg/day) while EPA is consumed at the level of approximately 50 mg/day in a typical North American diet.

DHA plus EPA are absent from plant food sources rich in ALA (such as flax, canola oil, and walnuts). Since the metabolic conversion of ALA to DHA/EPA (combined) by metabolism is very limited in humans, the most direct way of providing DHA plus EPA for the body is via their direct consumption. Current intakes of DHA are approximately 20% of the target (300 mg/day) suggested by an expert scientific group during pregnancy and lactation. The extremely low intake of DHA in young children (e.g., approximately 19 mg DHA/day on average for 3-yr. olds in North America ) is also of particular concern. Current intakes of DHA/EPA (combined) of 130 mg/day are approximately 15% of the target (900 mg/day) officially recommended by the American Heart Association for those with coronary heart disease and 20% of the 650 mg/day advised by an expert scientific group for healthy individuals. In view of the widespread reluctance of the public to consume sufficient amounts of fish, functional foods containing DHA plus EPA will become increasingly important sources of these important nutrients in the coming years to support optimal brain/visual performance, for cardio care, and other health conditions for young and old alike.

(end of article)

What’s important to note from this article is that Omega-3s are essential foods needed for health and especially needed for optimal health. You just can’t live well without it. As kids and teenagers, our bodies seem for the most part, indestructible. The life force is strong and abundant. You see this every Spring, when the grasses and weeds begin to grow. You can plaster concrete 8 inches deep and lo and behold within a short amount of time, grass finds its way through the cracks and crevices seeking sunlight and oxygen. So it is in the Spring time of youth, we find ourselves more powerful than a speeding locomotive, we feel like we can leap over tall buildings with a single bound. Yes, we are super men and women in the prime of life.

However, time marches forward and our bodies begin to wear. Certain stresses on the body begin to take their toll and the death knell begins and the doomsday clock edges closer to our own human demise.

Recently I was at an event of baby boomers. Now some were well worn from years of toil and labor, years of drinking and smoking, years of ingesting the American diet. It showed clearly in the waistlines, the sagging neck lines. Turtlenecks were needed to cover the turtle necks, if you know what I mean. But some boomers, some but not all, wore their age extremely well. Some were fit and toned. Some were energetic and exuberant. They were not indulging themselves in gluttony. They were sleeping early and early to rise o the hotel’s gym. They were sensible in what they ate and in what they drank.

All these observations were meaningful in that the sins of neglect are painted with thick lines on the bodies of those who thought they still had time to make the changes, only to find out they were just a little too late, a little too tired, and a little too sick.

My obvious point is to take care of yourself today and this week, this month, this year. Today is the only day you can live so make the commitment to live it well. Keep it real. My little trick is to tie the behaviors to triggers. Every time I get hungry, I go for my supplements first make sure I take all the appropriate vitamins and minerals I am working on and then I find a nutritious snack or meal to the extent that circumstances allow.

Do first things first, like taking Calamarine everyday. It’s the daily doing of simple things that can yield extraordinary results.

-Garey

Here is where calamarine comes in handy.

I will quote from a health blog I frequent:

http://soursally.info/healthy-food-for-your-eyes/

The same healthy diet that’s good for your heart and arteries can help preserve your eyes and vision.That’s not surprising. “Vision depends on tiny capillaries that supply the retina and other parts of the eye with nutrients and oxygen,” says Monique Roy, MD, a professor at the New Jersey Medical School’s Institute of Ophthalmology and Visual Science. “Keeping those arteries healthy is essential.”

As part of an overall healthy diet, several key nutrients appear to be particularly important to preserving sight as we get older.

C, E, and Zinc:-

A decade ago, the Age-Related Eye Disease Study reported that people given vitamin E, vitamin C, beta carotene, and zinc in supplements were less likely to develop advanced age-related macular degeneration, or AMD. The combination was most effective at slowing the progression from intermediate to advanced AMD, which is one of the leading causes of age-related blindness. Because of those findings, many people diagnosed with early signs of AMD today are routinely prescribed a pill that combines these nutrients.

Lutein and Zeaxanthin:-

Two other nutrients – lutein and zeaxanthin – are also linked to lower risk of macular degeneration and cataracts. A 2008 Tufts University study of 1,802 women 50 to 79 years old found that those who consumed the most lutein and zeaxanthin in their diets were 23% less likely to develop cataracts than those who consumed the least. Rich sources of these two compounds include kale, spinach, turnip greens, romaine lettuce, broccoli, and Brussels sprouts.

Omega-3 Fatty Acid:-

The newest nutrient linked to better vision with age is omega-3 fatty acid, which is found predominantly in fish oil. In a study of 2,520 people, researchers at Johns Hopkins University reported in 2010 that people who consumed fish high in omega-3s fatty acids often were significantly less likely to have advanced age-related macular degeneration. Omega-3s may also protect against cataracts, according to 2010 findings by researchers at the Clinical University of Navarra in Spain.

Researchers don’t understand exactly why omega-3s may protect against eye diseases. One guess is that these healthy oils may reduce inflammation and thereby protect against cell damage.

Pills vs. Food:-

Although antioxidant supplements are routinely prescribed to people with early signs of macular degeneration, there’s little agreement on whether supplements will help otherwise healthy people preserve their vision. “Most of the evidence to date is very mixed,” Allen Taylor, a leading researcher at the Laboratory for Nutrition and Vision Research at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, tells WebMD. In one recent study, for example, a multivitamin seemed to protect against some forms of cataracts but actually raise the risk of other forms.

“By far the best way to protect your vision from age-related diseases is by eating a healthy diet,” says Kathleen Zelman, RD, director of nutrition for WebMD.

Recent findings help make the case for healthy food choices. A 2010 study by French scientists, for instance, found eating more vegetables – including cabbage, broccoli, pepper, corn, or spinach – improved the condition of the retina in people with age-related macular degeneration.

On the event of his 70th birthday Mark Twain said, “If you want to maintain your health, eat want you don’t want, drink what you don’t like and do what you’d druther not.”

Dr. Michelle Price Judge, a faculty member at the University of Connecticut School of Nursing, is keenly interested in how omega-3 fatty acids consumed during pregnancy impact both maternal and infant health. She has demonstrated previously that maternal consumption of docosahexaenoic acid (DHA; a prominent omega-3 fatty acid) during pregnancy gives infants a developmental advantage even 9 months after they are born. These findings prompted her to consider the benefits that DHA could holistically have on the maternal-infant dyad. Specifically, might greater omega-3 fatty acid intake during pregnancy lower risk for postpartum depression, a condition that leads to a multitude of problems including interruptions in maternal-infant attachment and subsequent impairments in later infant development? As part of the scientific program of the American Society for Nutrition, results from this study will be presented on April 12 at the Experimental Biology 2011 meeting in Washington, DC.

To answer this question, Dr. Judge oversaw a randomized, double-blind, placebo-controlled dietary intervention trial in which 52 pregnant women took either a placebo (corn oil) or a fish oil capsule containing 300 milligrams of DHA 5 days each week from 24-40 weeks of pregnancy. This is the amount a woman would consume if she ate about ½ serving of salmon. It is noteworthy that dietary DHA intake during pregnancy has been estimated to be 50-70 milligrams of DHA daily: a mere fraction of the 200 milligrams daily that is considered optimal during pregnancy by most experts. Using the Postpartum Depression Screening Scale developed by her colleague and coauthor Dr. Cheryl Beck, Judge was able to categorize postpartum women as having negligible depressive symptoms, significant symptoms of postpartum depression, or being “positive” for this condition. The Postpartum Depression Screening Scale also assisted the research team in discerning between several symptoms specific to the disorder including sleeping/eating disturbances, anxiety, emotional liability, confusion, loss of self, guilt, and thoughts of suicide.

Although the study did not have enough women to investigate if fish oil consumption resulted in a lower incidence of diagnosable postpartum depression, women in the treatment group had significantly lower total Postpartum Depression Screening Scale scores, with significantly fewer symptoms common to postpartum depression. For example, compared to those in the control group, women in the fish oil group were less likely to report symptoms related to anxiety and loss of self.

Judge and coworkers concluded “DHA consumption during pregnancy – at levels that are reasonably attained from foods – has the potential to decrease symptoms of postpartum depression.” Why is this important? For starters, some experts estimate that postpartum depression affects a whopping 25% of new mothers. And healthcare providers agree that this condition can have devastating consequences, not only for the women experiencing it but also for their children and family.

The bottom line? Although larger-scale intervention studies will be needed to better understand the mechanisms and magnitude by which fish oil consumption can improve postpartum mental health, women would be wise to eat at least a serving of high-omega-3 fish 2-3 days per week. Although fish oil supplements may be more acceptable to some women, the real thing is clearly the more nutritious option as a serving of fish is also protein- and mineral-rich. Clearly, fish as a “brain food” is gaining the nod from not only from the general public, but scientists as well.”

Contact: Suzanne Price
sprice@nutrition.org
Federation of American Societies for Experimental Biology

It cites a new study that shows pronounced effects of DHA omega-3 on postpartum depression following birth.

According to a new study, the consumption of fish oil which has omega-3 fatty acid during pregnancy may retard postpartum depression in women.

In the research, 52 pregnant women took placebo or fish oil capsules containing 300 milligrams of docosahexaenoic acid which is a prominent of omega-3 fatty acid, five days a week, each week from weeks 24 to 40 of pregnancy.

After giving birth, the women were tested for symptoms of postpartum depression which includes sleeping, anxiety, eating problems, emotional issues, confusion and thoughts of suicide, but fewer symptoms were found in those that took the capsules than those that took the placebo.

Dr. Michelle Price Judge, of the University of Connecticut School of Nursing, and colleagues, reported that there were not enough women to validate whether the DHA was responsible for the reduction.

However, Dr. Shari I. Lusskin, director of reproductive psychiatry at NYU Langone Medical Center in New York City, has stated the need of the study to be revised on” a larger scale ,with proper controls for a number of medical and psychosocial factors before concluding that omega-3 fatty acid consumption lowers the risk of postpartum depression” .

Moreover, she has recommended a healthy diet for a pregnant woman and her developing baby, as postpartum depression is said to affect 25% of new mothers.

What could be easier than taking a couple of positively safe DHA Omega-3 capsules? No taste to worry about. No after burp to worry about, and now a reduced risk of postpartum depression.

Take action.

CSI:USA – Death on the Loose.

In my talk today I have 3 points for you to GRAVELY consider:

First There is a large and lurking danger for everyone in this room.

Second I WILL GIVE YOU A very quick way to assess your risk

Third A message of hope. Don’t be a fatalist: Prevention and Reversal of Heart Disease is a lot simpler than you think.

THREE NUMBERS TO REMEMBER – FIRST NUMBER 81 MILLION

The National Institute of Health NIH.gov: states Cardiovascular Disease Statistics Estimates for the year 2007 are that 81,100,000 people in the United States have one or more forms of cardiovascular disease (CVD).

SECOND NUMBER 1.1 MILLION
More than 1.1 million people experience a heart attack (myocardial infarction) each year, and for many of them, the heart attack is their first symptom of coronary artery disease. This means that every 28 seconds there is a heart attack in the United States.

Cedars Sinai. Edu DEFINES A heart attack or myocardial infarction is a medical emergency in which the supply of blood to the heart is suddenly and severely reduced or cut off, causing the muscle to die from lack of oxygen. Guess how many of those heart attacks are fatal? 10%, 20%, 30% Half of them?  If you guessed half, you are right.

THIRD NUMBER 500,000. HALF A MILLION
According to CedarSinai.edu, 500,000 heart attack victims with end up in the mortuary this year.  That means about one fatality from heart attack every single minute. 1,440 deaths by heart attack per day in the United States.  BY CONTRAST FBI.GOV REPORTS THERE ARE 37 HOMICIDES PER DAY IN THE US. 1,440 deaths per day from heart attack. 37 deaths per day from heart attack. We hear about the latter on the news daily, why not the former?

Heart disease isn’t just a man’s disease. Heart attack, stroke and other cardiovascular diseases are DEVASTATING TO WOMEN, too. Many women believe that cancer is more of a threat. How many believe that? CANCER OR HEART DISEASE? In fact, coronary heart disease, which causes heart attack, is the single leading cause of death for American women. Nearly twice as many women in the United States die of heart disease, stroke and other cardiovascular diseases as from all forms of cancer, including breast cancer. (womensheart.org)

NOW YOU YOUNGER PEOPLE think that heart disease is for the older folks. the older you get the more likely you are to suffer from heart disease but would it shock you to know that THE AMERICAN SOCIETY OF PEDIATRICIANS IN ITS 2009 JOURNAL URGES the prescription of STATINS TO KIDS as young as eight years OLD?  Teens are showing up at emergency rooms presenting with heart attacks. SOME,not all, doctors are prescribing statin drugs to kids as young as eight years old. Controversial, yes, but WOW.

I HAVE A HANDOUT TO GIVE YOU AT THE END. IN AN ARTICLE ENTITLED The “MacStatin”: Fast food with some ketchup, salt, and a statin to go August 13, 2010 | Michael O’Riordan shows the lack of willingness to change lifestyle and junk food habits leads to obesity, diabetes and heart disease.

CONSIDERING WHAT I HAVE READ ABOUT STATIN DRUGS, IF THE HEART ATTACK DOESN’T GET YOU THE TREATMENT WILL. Dr. Ray Hinesh WCBM radio host Sunday’s at 10 am. HIS WEBSITE www.illnessisoptional.com REVEALS A list of statin side effects and how much greater AND more PERVASIVE THEY ARE than the benefits statins are expected and presumed to provide.

SO WHAT CAN YOU A PERSON DO?
NUMBER 2: YOUR JOB IS TO  GET A RISK ASSESSMENT

I don’t have to tell you that

• Smoking
• high blood pressure
• systemic inflammation
• diabetes
• being overweight or obese
• physical inactivity
• LEADS TO HEART DISEASE

Go to www.americanheart.org and take the four step risk assessment test. Know your risks. Being aware is about 50% of the battle. You may know that almost half of heart attacks end up being fatal. What you may not know is that almost fifty percent of first time heart attacks victims had no clue that they had heart disease. So the heart attack winds up being their first ever diagnosis or acknowledgment that a problem even exists. Knowing your risks, improves your chances by a mile and a half. 

Number 3: Prevention is BETTER THAN CURE. A STITCH IN TIME SAVES NINE.

Let me give you a shortcut to preventing and reversing heart disease, that has taken me six years to learn:

TWO VITAMINS AND A SUPER FOOD.  TWO VITAMINS AND A SUPER FOOD.

SUPER FOOD: HIGH POTENCY EPA/DHA OMEGA-3, VITAMIN K2, VITAMIN D3. I WILL SPEAK ABOUT OMEGA-3.

While there are great risks HEART DISEASE AND with certain pharmaceutical drugs, there are ONLY great benefits of Omega-3 fish oil in preventing heart ailments. THESE have been proven through literally thousands of clinical trials. Let me quote this abstract from the Mayo clinic.

Mayo Clinic 2000 Jun; From Inuit to implementation: omega-3 fatty acids come of age. Abstract

The cardiovascular effects of marine omega-3  fatty acids.  In the late 1970s, epidemiological studies revealed that Greenland Inuits had substantially reduced rates of acute myocardial infarction compared with Western control subjects. These observations generated more than 4,500 studies to explore this and other effects of omega-3 fatty acids on human metabolism and health. AN ITALIAN Prevention study of 11,324 patients showed a 45% decrease in risk of sudden cardiac death and a 20% reduction in all-cause mortality in the group taking 850 mg/d of omega-3 fatty acids. These fatty acids have potent anti-inflammatory effects. 3 to 5 g/ d can reduce triglyceride levels by 30% to 50%, minimizing the risk of coronary heart disease.

LET ME CONCLUDE BY SAYING

Your Heart

• Works hard every moment, of every day.
• Never takes a day off.
• Never calls in sick.
• Morning, noon and night, your heart is no slacker.
• Shouldn’t you take good care of this tireless servant?
• If you are at all concerned about heart health then take note:
• The secret of preventing and beating heart disease BEGINS WITH Omega-3s!
  I am a five year veteran of taking Omega-3 capsules.
  I witnessed this in my own life.
• Normalized cholesterol, triglycerides in check. Yes!
• Take enough Omega-3s and prevent/reverse heart disease.

In summary:

1. THERE IS A CLEAR AND PRESENT DANGER OF HEART ATTACKS AND HEART DISEASE IN OUR COUNTRY.
2. YOU CAN DO A RISK SELF ASSESSMENT IN 10 MINUTES ON AMERICANHEART.ORG
3. PREVENTION IS BETTER THAN CURE.

As a businessman I always think about ROI, return on investment.

Without your health you have nothing.

Take good care of your heart and your heart will take good care of you.

Learn More about N3, K2, D3 Solution to Heart Disease. (coming soon)

Derived from the byproducts of food-grade calamari (Cephalopoda), Calamarine™ Omega-3 oils offer a highly sustainable and environmentally friendly alternative. Calamari naturally contains high levels of docosahexaenoic acid (DHA). An increasing body of research supports DHA as the more efficacious option for addressing most of the common health conditions supported by Omega-3 supplementation.

“Calamarine™ represents the culmination of years of research to discover a sustainable Omega-3 source that would provide a more potent and efficacious fatty acid composition.” said Gjendemsjø. “We set out to create a sustainably sourced marine DHA ingredient that would be competitive with other marine DHA sources. To be able to say that we have now succeeded is really satisfying to me and the entire Pharma Marine team”   Calamarine™ production uses vastly improved Omega-3 purification procedures.

The combination of a highly experienced production team and state-of-the-art technology yields superior taste and smell characteristics as well as improved ingredient stability. The unique characteristics embodied in Calamarine™ offers our customers opportunities to differentiate themselves in the increasingly commoditized Omega-3 market.

About Pharma Marine Group Pharma Marine’s new manufacturing facility is located on the west coast of Norway, near Aalesund, a region where refining marine oils dates back more than 130 years, and now accounts for 40% of the world’s high-grade Omega-3 output. In addition to advanced purification technologies, the facility houses a state-of-the-art research laboratory where several market-changing, patent protected innovations are being developed. Pharma Marine Group is the only supplier of Calamari derived Omega-3 concentrates.

Go to Calamarine.com to learn more about Calamarine uses.

High DHA OMEGA-3: A superb concentration of Omega-3 with a heavy concentration on the DHA component.

As a certified fitness trainer, I personally recommend all my friends, family members and clients to take Omega-3s daily. It’s what we call a “gateway activity.” It opens up healthful living in ways you really can’t imagine. If you give your body the right materials to work with, it can operate at a higher level.  Let’s just call it optimal for now. If I use too many superlatives, you may not believe me!

If you use the word CALAMARINE in the coupon box on checkout, you will receive a previously unannounced discount of 15% off!

Try it! -Garey Simmons, AFAA